Jonathan Wooten, Ph.D., M.S.

Jonathan Wooten
Jonathan Wooten, Ph.D., M.S.
Entry Year
2022
Phone
240-276-5626

Doctoral Degree

Ph.D., Pharmacology, Loma Linda University (2022)

Master's Degrees

  • M.P.H., Applied Biostatistics and Epidemiology Track, Yale University (exp. 2023)
  • M.S., Chemistry, Georgia State University (2015)

Research Interests

Breast Cancer; Prostate Cancer; Cancer Epidemiology; Cancer Health Disparities; Drug Discovery, Design, Development; Phytochemicals; Natural Products

Publications

Mavingire N, Campbell P, Liu T, Wooten J, Khan S, Chen X, Matthews J, Wang C, Brantley E. Aminoflavone upregulates putative tumor suppressor miR-125b-2-3p to inhibit luminal A breast cancer stem cell-like properties. Precis Clin Med. 2022 Mar 28;5(2):pbac008. doi: 10.1093/pcmedi/pbac008. eCollection 2022 Jun. PMID: 35694715.

Wooten J, Mavingire N, Araújo CA, Aja J, Wauchope S, Delgoda R, Brantley E. Dibenzyl trisulfide induces caspase-independent death and lysosomal membrane permeabilization of triple-negative breast cancer cells. Fitoterapia. 2022 Jul;160:105203. doi: 10.1016/j.fitote.2022.105203. Epub 2022 Apr 27. PMID: 35489582.

Mavingire N, Campbell P, Wooten J, Aja J, Davis MB, Loaiza-Perez A, Brantley E. Cancer stem cells: Culprits in endocrine resistance and racial disparities in breast cancer outcomes. Cancer Lett. 2021 Mar 1;500:64-74. doi: 10.1016/j.canlet.2020.12.014. Epub 2020 Dec 9. PMID: 33309858.

Rowland LK, Campbell PS, Mavingire N, Wooten JV, McLean L, Zylstra D, Thorne G, Daly D, Boyle K, Whang S, Unternaehrer J, Brantley EJ. Putative tumor suppressor cytoglobin promotes aryl hydrocarbon receptor ligand-mediated triple negative breast cancer cell death. J Cell Biochem. 2019 Apr;120(4):6004-6014. doi: 10.1002/jcb.27887. Epub 2018 Nov 18. PMID: 30450577.

Campbell PS, Mavingire N, Khan S, Rowland LK, Wooten JV, Opoku-Agyeman A, Guevara A, Soto U, Cavalli F, Loaiza-Pérez AI, Nagaraj G, Denham LJ, Adeoye O, Jenkins BD, Davis MB, Schiff R, Brantley EJ. AhR ligand aminoflavone suppresses α6-integrin-Src-Akt signaling to attenuate tamoxifen resistance in breast cancer cells. J Cell Physiol. 2018 Jan;234(1):108-121. doi: 10.1002/jcp.27013. Epub 2018 Aug 4. PMID: 30076704.

Badal SAM, Asuncion Valenzuela MM, Zylstra D, Huang G, Vendantam P, Francis S, Quitugua A, Amis LH, Davis W, Tzeng TJ, Jacobs H, Gangemi DJ, Raner G, Rowland L, Wooten J, Campbell P, Brantley E, Delgoda R. Glaucarubulone glucoside from Castela macrophylla suppresses MCF-7 breast cancer cell growth and attenuates benzo[a]pyrene-mediated CYP1A gene induction. J Appl Toxicol. 2017 Jul;37(7):873-883. doi: 10.1002/jat.3436. Epub 2017 Jan 31. PMID: 28138972.