Lauren Hurwitz, Ph.D., M.H.S.

Lauren Hurwitz, Ph.D., M.H.S.
Division of Cancer Epidemiology and Genetics (DCEG)
Entry Year

Doctoral Degree

Ph.D., Cancer Epidemiology, Johns Hopkins University (2018)

Master's Degree

M.H.S., Johns Hopkins University (2013)

Research Interests

Modifiable Risk Factors for Primary and Secondary Cancer Prevention

Primary Preceptor/Branch

Stella Koutros, Ph.D., M.P.H., Occupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology & Genetics (DCEG)


Robsahm TE, Tsuruda KM, Hektoen HH, Storås AH, Cook MB, Hurwitz LM, Langseth H. Applying recommended definition of aggressive prostate cancer: a validation study using high-quality data from the Cancer Registry of Norway. Acta Oncol. 2023 Feb 10;:1-7. doi: 10.1080/0284186X.2023.2175331. [Epub ahead of print] PubMed PMID: 36762472.

Watts EL, Perez-Cornago A, Fensom GK, Smith-Byrne K, Noor U, Andrews CD, Gunter MJ, Holmes MV, Martin RM, Tsilidis KK, Albanes D, Barricarte A, Bueno-de-Mesquita HB, Cohn BA, Deschasaux-Tanguy M, Dimou NL, Ferrucci L, Flicker L, Freedman ND, Giles GG, Giovannucci EL, Haiman CA, Hankey GJ, Holly JMP, Huang J, Huang WY, Hurwitz LM, Kaaks R, Kubo T, Le Marchand L, MacInnis RJ, Männistö S, Metter EJ, Mikami K, Mucci LA, Olsen AW, Ozasa K, Palli D, Penney KL, Platz EA, Pollak MN, Roobol MJ, Schaefer CA, Schenk JM, Stattin P, Tamakoshi A, Thysell E, Tsai CJ, Touvier M, Van Den Eeden SK, Weiderpass E, Weinstein SJ, Wilkens LR, Yeap BB, Allen NE, Key TJ, Travis RC. Circulating insulin-like growth factors and risks of overall, aggressive and early-onset prostate cancer: a collaborative analysis of 20 prospective studies and Mendelian randomization analysis. Int J Epidemiol. 2023 Feb 8;52(1):71-86. doi: 10.1093/ije/dyac124. PubMed PMID: 35726641; PubMed Central PMCID: PMC9908067.

Hurwitz LM, Townsend MK, Jordan SJ, Patel AV, Teras LR, Lacey JV Jr, Doherty JA, Harris HR, Goodman MT, Shvetsov YB, Modugno F, Moysich KB, Robien K, Prizment A, Schildkraut JM, Berchuck A, Fortner RT, Chan AT, Wentzensen N, Hartge P, Sandler DP, O'Brien KM, Anton-Culver H, Ziogas A, Menon U, Ramus SJ, Pearce CL, Wu AH, White E, Peters U, Webb PM, Tworoger SS, Trabert B. Modification of the Association Between Frequent Aspirin Use and Ovarian Cancer Risk: A Meta-Analysis Using Individual-Level Data From Two Ovarian Cancer Consortia. J Clin Oncol. 2022 Dec 20;40(36):4207-4217. doi: 10.1200/JCO.21.01900. Epub 2022 Jul 22. PubMed PMID: 35867953; PubMed Central PMCID: PMC9916035.

Watts EL, Perez-Cornago A, Fensom GK, Smith-Byrne K, Noor U, Andrews CD, Gunter MJ, Holmes MV, Martin RM, Tsilidis KK, Albanes D, Barricarte A, Bueno-de-Mesquita B, Chen C, Cohn BA, Dimou NL, Ferrucci L, Flicker L, Freedman ND, Giles GG, Giovannucci EL, Goodman GE, Haiman CA, Hankey GJ, Huang J, Huang WY, Hurwitz LM, Kaaks R, Knekt P, Kubo T, Langseth H, Laughlin G, Le Marchand L, Luostarinen T, MacInnis RJ, Mäenpää HO, Männistö S, Metter EJ, Mikami K, Mucci LA, Olsen AW, Ozasa K, Palli D, Penney KL, Platz EA, Rissanen H, Sawada N, Schenk JM, Stattin P, Tamakoshi A, Thysell E, Tsai CJ, Tsugane S, Vatten L, Weiderpass E, Weinstein SJ, Wilkens LR, Yeap BB, Allen NE, Key TJ, Travis RC. Circulating free testosterone and risk of aggressive prostate cancer: Prospective and Mendelian randomisation analyses in international consortia. Int J Cancer. 2022 Oct 1;151(7):1033-1046. doi: 10.1002/ijc.34116. Epub 2022 Jun 7. PubMed PMID: 35579976; PubMed Central PMCID: PMC7613289.

Hurwitz LM, Shadyab AH, Tabung FK, Anderson GL, Saquib N, Wallace RB, Wild RA, Pfeiffer RM, Xu X, Trabert B. Analgesic Use and Circulating Estrogens, Androgens, and Their Metabolites in the Women's Health Initiative Observational Study. Cancer Prev Res (Phila). 2022 Mar 1;15(3):173-183. doi: 10.1158/1940-6207.CAPR-21-0264. PubMed PMID: 34893532; PubMed Central PMCID: PMC8898279.

Hurwitz LM, Pinsky PF, Trabert B. General population screening for ovarian cancer. Lancet. 2021 Jun 5;397(10290):2128-2130. doi: 10.1016/S0140-6736(21)01061-8. Epub 2021 May 12. PubMed PMID: 33991478.

Hurwitz LM, Agalliu I, Albanes D, Barry KH, Berndt SI, Cai Q, Chen C, Cheng I, Genkinger JM, Giles GG, Huang J, Joshu CE, Key TJ, Knutsen S, Koutros S, Langseth H, Li SX, MacInnis RJ, Markt SC, Penney KL, Perez-Cornago A, Rohan TE, Smith-Warner SA, Stampfer MJ, Stopsack KH, Tangen CM, Travis RC, Weinstein SJ, Lang PhD W, Jacobs EJ, Mucci LA, Platz EA, Cook MB. Recommended Definitions of Aggressive Prostate Cancer for Etiologic Epidemiologic Research. J Natl Cancer Inst. 2021 Jun 1;113(6):727-734. doi: 10.1093/jnci/djaa154. PubMed PMID: 33010161; PubMed Central PMCID: PMC8248961.

Tang W, Fowke JH, Hurwitz LM, Steinwandel M, Blot WJ, Ambs S. Aspirin Use and Prostate Cancer among African-American Men in the Southern Community Cohort Study. Cancer Epidemiol Biomarkers Prev. 2021 Mar;30(3):539-544. doi: 10.1158/1055-9965.EPI-19-0792. Epub 2020 Dec 8. PubMed PMID: 33293340; PubMed Central PMCID: PMC8049943.

Hurwitz LM, Michels KA, Cook MB, Pfeiffer RM, Trabert B. Associations between daily aspirin use and cancer risk across strata of major cancer risk factors in two large U.S. cohorts. Cancer Causes Control. 2021 Jan;32(1):57-65. doi: 10.1007/s10552-020-01357-2. Epub 2020 Oct 26. PubMed PMID: 33104910; PubMed Central PMCID: PMC7855934.

Cook MB, Hurwitz LM, Geczik AM, Butler EN. An Up-to-date Assessment of US Prostate Cancer Incidence Rates by Stage and Race: A Novel Approach Combining Multiple Imputation with Age and Delay Adjustment. Eur Urol. 2021 Jan;79(1):33-41. doi: 10.1016/j.eururo.2020.09.041. Epub 2020 Oct 20. PubMed PMID: 33092896; PubMed Central PMCID: PMC8853735.

Caumont F, Conti G, Hurwitz LM, Kuo C, Levie KE, Badiozamani K, Frankel JK, Flores JP, Brand TC, Chaurasia A, Rosner IL, Stroup SP, Musser JE, Cullen J, Porter CR. A prospective analysis of health-related quality of life in intermediate and high-risk prostate cancer patients managed with intensity modulated radiation therapy, with vs. without hormonal therapy. Urol Oncol. 2020 Oct;38(10):794.e1-794.e9. doi: 10.1016/j.urolonc.2020.02.007. Epub 2020 Mar 3. PubMed PMID: 32139288.

Hurwitz LM, Pinsky PF, Huang WY, Freedman ND, Trabert B. Aspirin use and ovarian cancer risk using extended follow-up of the PLCO Cancer Screening Trial. Gynecol Oncol. 2020 Nov;159(2):522-526. doi: 10.1016/j.ygyno.2020.08.038. Epub 2020 Sep 10. PubMed PMID: 32919779; PubMed Central PMCID: PMC7584756.

Hurwitz LM, Kulac I, Gumuskaya B, Valle JABD, Benedetti I, Pan F, Liu JO, Marrone MT, Arnold KB, Goodman PJ, Tangen CM, Lucia MS, Thompson IM, Drake CG, Isaacs WB, Nelson WG, De Marzo AM, Platz EA. Use of Aspirin and Statins in Relation to Inflammation in Benign Prostate Tissue in the Placebo Arm of the Prostate Cancer Prevention Trial. Cancer Prev Res (Phila). 2020 Oct;13(10):853-862. doi: 10.1158/1940-6207.CAPR-19-0450. Epub 2020 Jun 24. PubMed PMID: 32581009; PubMed Central PMCID: PMC7541466.

Hurwitz LM, Yeboah ED, Biritwum RB, Tettey Y, Adjei AA, Mensah JE, Tay E, Okyne V, Truelove A, Kelly SP, Zhou CK, Butler EN, Hoover RN, Hsing AW, Cook MB. Overall and abdominal obesity and prostate cancer risk in a West African population: An analysis of the Ghana Prostate Study. Int J Cancer. 2020 Nov 15;147(10):2669-2676. doi: 10.1002/ijc.33026. Epub 2020 May 6. PubMed PMID: 32350862; PubMed Central PMCID: PMC7530105.

Alsinnawi M, Cullen J, Hurwitz LM, Levie KE, Burns JF, Rosner IL, Brand TC, Stroup S, Sterbis JR, Rice K, Conti G, Porter CR. A prospective study of health-related quality of life outcomes among men treated for intermediate- and high-risk prostate cancer: the impact of primary and secondary therapies. Can J Urol. 2019 Aug;26(4):9809-9820. PubMed PMID: 31469635.

Burns JF, Hurwitz LM, Levie KE, Caumont F, Brand TC, Rosner IL, Stroup S, Musser JE, Cullen J, Porter CR. Impact of Subsequent Biopsies on Comprehensive Health Related Quality of Life in Patients with and without Prostate Cancer. J Urol. 2019 May;201(5):916-922. doi: 10.1097/JU.0000000000000024. PubMed PMID: 30676475.

Hurwitz LM, Joshu CE, Barber JR, Prizment AE, Vitolins MZ, Jones MR, Folsom AR, Han M, Platz EA. Aspirin and Non-Aspirin NSAID Use and Prostate Cancer Incidence, Mortality, and Case Fatality in the Atherosclerosis Risk in Communities Study. Cancer Epidemiol Biomarkers Prev. 2019 Mar;28(3):563-569. doi: 10.1158/1055-9965.EPI-18-0965. Epub 2018 Nov 28. PubMed PMID: 30487131; PubMed Central PMCID: PMC6401240.

Salter CA, Cullen J, Kuo C, Chen Y, Hurwitz L, Metwalli AR, Dimitrakoff J, Rosner IL. Alkaline Phosphatase Kinetics Predict Metastasis among Prostate Cancer Patients Who Experience Relapse following Radical Prostatectomy. Biomed Res Int. 2018;2018:4727089. doi: 10.1155/2018/4727089. eCollection 2018. PubMed PMID: 30050933; PubMed Central PMCID: PMC6046170.

Hurwitz LM, Cullen J. Reply to Prostate cancer multidisciplinary clinic and decisional regret: Looking for a longer follow-up. Cancer. 2017 Dec 15;123(24):4937-4939. doi: 10.1002/cncr.31053. Epub 2017 Oct 4. PubMed PMID: 28976542.

Hurwitz LM, Cullen J, Kim DJ, Elsamanoudi S, Hudak J, Colston M, Travis J, Kuo HC, Rice KR, Porter CR, Rosner IL. Longitudinal regret after treatment for low- and intermediate-risk prostate cancer. Cancer. 2017 Nov 1;123(21):4252-4258. doi: 10.1002/cncr.30841. Epub 2017 Jul 5. PubMed PMID: 28678408.

Hammerich KH, Donahue TF, Rosner IL, Cullen J, Kuo HC, Hurwitz L, Chen Y, Bernstein M, Coleman J, Danila DC, Metwalli AR. Alkaline phosphatase velocity predicts overall survival and bone metastasis in patients with castration-resistant prostate cancer. Urol Oncol. 2017 Jul;35(7):460.e21-460.e28. doi: 10.1016/j.urolonc.2017.02.001. Epub 2017 Apr 11. PubMed PMID: 28410987.

Banerji JS, Hurwitz LM, Cullen J, Wolff EM, Levie KE, Rosner IL, Brand TC, LʼEsperance JO, Sterbis JR, Porter CR. A prospective study of health-related quality-of-life outcomes for patients with low-risk prostate cancer managed by active surveillance or radiation therapy. Urol Oncol. 2017 May;35(5):234-242. doi: 10.1016/j.urolonc.2016.12.015. Epub 2017 Jan 19. PubMed PMID: 28110975.

Pham KN, Cullen J, Hurwitz LM, Wolff EM, Levie KE, Odem-Davis K, Banerji JS, Rosner IL, Brand TC, L'Esperance JO, Sterbis JR, Porter CR. Prospective Quality of Life in Men Choosing Active Surveillance Compared to Those Biopsied but not Diagnosed with Prostate Cancer. J Urol. 2016 Aug;196(2):392-8. doi: 10.1016/j.juro.2016.02.2972. Epub 2016 Mar 11. PubMed PMID: 26976206.

Hurwitz LM, Cullen J, Elsamanoudi S, Kim DJ, Hudak J, Colston M, Travis J, Kuo HC, Porter CR, Rosner IL. A prospective cohort study of treatment decision-making for prostate cancer following participation in a multidisciplinary clinic. Urol Oncol. 2016 May;34(5):233.e17-25. doi: 10.1016/j.urolonc.2015.11.014. Epub 2015 Dec 15. PubMed PMID: 26705101.

Kim DJ, Hawksworth DJ, Hurwitz LM, Cullen J, Rosner IL, Lue TF, Dean RC. A prospective, randomized, placebo-controlled trial of on-Demand vs. nightly sildenafil citrate as assessed by Rigiscan and the international index of erectile function. Andrology. 2016 Jan;4(1):27-32. doi: 10.1111/andr.12118. Epub 2015 Dec 10. PubMed PMID: 26663669.

Jeldres C, Cullen J, Hurwitz LM, Wolff EM, Levie KE, Odem-Davis K, Johnston RB, Pham KN, Rosner IL, Brand TC, L'Esperance JO, Sterbis JR, Etzioni R, Porter CR. Prospective quality-of-life outcomes for low-risk prostate cancer: Active surveillance versus radical prostatectomy. Cancer. 2015 Jul 15;121(14):2465-73. doi: 10.1002/cncr.29370. Epub 2015 Apr 6. PubMed PMID: 25845467; PubMed Central PMCID: PMC4490040.

Andreotti G, Karami S, Pfeiffer RM, Hurwitz L, Liao LM, Weinstein SJ, Albanes D, Virtamo J, Silverman DT, Rothman N, Moore LE. LINE1 methylation levels associated with increased bladder cancer risk in pre-diagnostic blood DNA among US (PLCO) and European (ATBC) cohort study participants. Epigenetics. 2014 Mar;9(3):404-15. doi: 10.4161/epi.27386. Epub 2013 Dec 6. PubMed PMID: 24316677; PubMed Central PMCID: PMC4053459.

Hurwitz LM, Heaphy CM, Joshu CE, Isaacs WB, Konishi Y, De Marzo AM, Isaacs SD, Wiley KE, Platz EA, Meeker AK. Telomere length as a risk factor for hereditary prostate cancer. Prostate. 2014 Apr;74(4):359-64. doi: 10.1002/pros.22755. Epub 2013 Nov 28. PubMed PMID: 24285042; PubMed Central PMCID: PMC4479489.